{"id":2910,"date":"2026-02-15T09:20:15","date_gmt":"2026-02-15T00:20:15","guid":{"rendered":"https:\/\/kpu-als.jp\/w\/?p=2910"},"modified":"2026-02-17T12:43:17","modified_gmt":"2026-02-17T03:43:17","slug":"%e5%ad%a6%e8%a1%93%e9%9b%91%e8%aa%8c%e3%80%8cinternational-journal-of-molecular-sciences%e3%80%8d%e3%81%ab%e5%b8%8c%e5%b0%91%e7%b3%96%e7%a0%94%e7%a9%b6%e3%81%ae%e6%88%90%e6%9e%9c%e3%81%8c%e6%8e%b2","status":"publish","type":"post","link":"https:\/\/kpu-als.jp\/w\/2026\/02\/%e5%ad%a6%e8%a1%93%e9%9b%91%e8%aa%8c%e3%80%8cinternational-journal-of-molecular-sciences%e3%80%8d%e3%81%ab%e5%b8%8c%e5%b0%91%e7%b3%96%e7%a0%94%e7%a9%b6%e3%81%ae%e6%88%90%e6%9e%9c%e3%81%8c%e6%8e%b2\/","title":{"rendered":"\u5b66\u8853\u96d1\u8a8c\u300cInternational Journal of Molecular Sciences\u300d\u306b\u5e0c\u5c11\u7cd6\u7814\u7a76\u306e\u6210\u679c\u304c\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\uff08\u52d5\u7269\u6a5f\u80fd\u5b66\u7814\u7a76\u5ba4\uff09"},"content":{"rendered":"<p><strong>\u9589\u7d4c\u5f8c\u306e\u904e\u5270\u306a\u7802\u7cd6\u6442\u53d6\u306f\u5185\u81d3\u80a5\u6e80\u30682<\/strong><strong>\u578b\u7cd6\u5c3f\u75c5\u3092\u5897\u60aa\u3055\u305b\u308b\u3053\u3068\u3092\u767a\u898b\uff01<\/strong><\/p>\r\n<p><strong>\u305d\u3057\u3066\u3001\u3053\u306e\u4e88\u9632\u306b\u5e0c\u5c11\u7cd6\u30a2\u30eb\u30ed\u30fc\u30b9\u304c\u6709\u52b9\uff01<\/strong><\/p>\r\n<p>&nbsp;<\/p>\r\n<p>\u5e73\u5747\u3057\u306650\u6b73\u524d\u5f8c\u3067\u8fce\u3048\u308b\u9589\u7d4c\u306b\u4f34\u3046\u5973\u6027\u30db\u30eb\u30e2\u30f3\uff1a\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u306e\u4f4e\u4e0b\u306f\u3001\u5185\u81d3\u8102\u80aa\u306e\u84c4\u7a4d\u3092\u4fc3\u9032\u3057\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3092\u4e0a\u6607\u3055\u305b\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u5973\u6027\u30db\u30eb\u30e2\u30f3\u306e\u88dc\u5145\u7642\u6cd5\u306f\u4e00\u5b9a\u306e\u6709\u52b9\u6027\u3092\u793a\u3059\u4e00\u65b9\u3067\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u3084\u4e73\u304c\u3093\u306a\u3069\u306e\u30ea\u30b9\u30af\u304c\u554f\u984c\u3067\u3059\u3002<\/p>\r\n<p>\u8fd1\u5e74\u3001\u8178\u30db\u30eb\u30e2\u30f3GLP-1\uff08\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9-1\uff09\u3092\u57fa\u76e4\u3068\u3057\u305f\u88fd\u5264\u304c\u3001\u65b0\u305f\u306a\u6297\u80a5\u6e80\u85ac\u30fb\u6297\u7cd6\u5c3f\u75c5\u85ac\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3001\u98df\u54c1\u6210\u5206\u3067\u3042\u308b\u5e0c\u5c11\u7cd6\u306eD-\u30a2\u30eb\u30ed\u30fc\u30b9\u304c\u3001\u7518\u5473\u3092\u6709\u3057\u3066\u30bc\u30ed\u30ab\u30ed\u30ea\u30fc\u3067\u3042\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001GLP-1\u5206\u6ccc\u4fc3\u9032\u4f5c\u7528\u3092\u6709\u3057\u307e\u3059\u3002\u3057\u304b\u3057\u3001D-\u30a2\u30eb\u30ed\u30fc\u30b9\u306e\u9589\u7d4c\u5f8c\u306e\u6709\u7528\u6027\u306b\u3064\u3044\u3066\u306f\u691c\u8a3c\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\r\n<p>\u3053\u306e\u5ea6\u3001\u4eac\u90fd\u5e9c\u7acb\u5927\u5b66\u5927\u5b66\u9662\u751f\u547d\u74b0\u5883\u79d1\u5b66\u7814\u7a76\u79d1\u52d5\u7269\u6a5f\u80fd\u5b66\u7814\u7a76\u5ba4\u6559\u6388\u306e\u5ca9\ufa11\u6709\u4f5c\u3001\u535a\u58eb\u5927\u5b66\u9662\u751f\u306e\u5c04\u5834\u62f3\u864e\u3001\u95a2\u897f\u96fb\u529b\u533b\u5b66\u7814\u7a76\u6240\u7d71\u5408\u751f\u7406\u5b66\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u9577\u306e\u77e2\u7530\u4fca\u5f66\u3092\u4e2d\u5fc3\u3068\u3059\u308b\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u9589\u7d4c\u5f8c\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u3068\u306a\u308b\u5375\u5de3\u6458\u51fa\u306e\u96cc\u30de\u30a6\u30b9\u3092\u7528\u3044\u3066\u3001\u4ee5\u4e0b\u306e\u4e8b\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002<\/p>\r\n<p>&nbsp;<\/p>\r\n<ol>\r\n\t<li><strong>\u9589\u7d4c\u5f8c\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u3067\u306f\u3001\u30b7\u30e7\u7cd6\u8ca0\u8377\u306b\u3088\u308a\u5185\u81d3\u8102\u80aa\u306e\u84c4\u7a4d\u304a\u3088\u3073\u8010\u7cd6\u80fd\u7570\u5e38\u304c\u5897\u60aa\u3057\u307e\u3057\u305f\u3002<\/strong><\/li>\r\n\t<li><strong>\u3053\u306e\u3088\u3046\u306a\u4ee3\u8b1d\u7570\u5e38\u306f\u3001\u5e0c\u5c11\u7cd6D-<\/strong><strong>\u30a2\u30eb\u30ed\u30fc\u30b9\u306e\u6442\u53d6\u306b\u3088\u308a\u6539\u5584\u3055\u308c\u307e\u3057\u305f\u3002<\/strong><\/li>\r\n\t<li><strong>\u3053\u308c\u3089\u306e\u6539\u5584\u52b9\u679c\u306f\u3001GLP-1<\/strong><strong>\u53d7\u5bb9\u4f53\u306e\u6d3b\u6027\u5316\u304c\u5fc5\u9808\u3067\u3042\u308b\u3068\u3044\u3046\u3001\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u89e3\u660e\u3057\u307e\u3057\u305f\u3002<\/strong><\/li>\r\n<\/ol>\r\n<p>&nbsp;<\/p>\r\n<p>50\u6b73\u4ee5\u964d\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u7f79\u60a3\u8005\u6570\u306f\u5897\u52a0\u3057\u3001\u7279\u306b\u5973\u6027\u3067\u306f\u9589\u7d4c\u306b\u4f34\u3046\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u4f4e\u4e0b\u304c\u305d\u306e\u4e00\u56e0\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u7814\u7a76\u306f\u3001\u7802\u7cd6\u306e\u7d99\u7d9a\u7684\u306a\u6442\u53d6\u304c\u9589\u7d4c\u5f8c\u306e2\u578b\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af\u3092\u3055\u3089\u306b\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u4e00\u65b9\u3001<u>\u540c\u3058\u7518\u5473\u3092\u3082\u3064\u5e0c\u5c11\u7cd6<\/u><u> D-<\/u><u>\u30a2\u30eb\u30ed\u30fc\u30b9 <\/u><u>\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u9589\u7d4c\u5f8c\u306b\u751f\u3058\u3084\u3059\u3044\u5185\u81d3\u80a5\u6e80\u30842<\/u><u>\u578b\u7cd6\u5c3f\u75c5\u3092\u4e88\u9632\u30fb\u6539\u5584\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3001\u52d5\u7269\u5b9f\u9a13\u304b\u3089\u793a\u3055\u308c\u307e\u3057\u305f\u3002D-<\/u><u>\u30a2\u30eb\u30ed\u30fc\u30b9\u306f\u3059\u3067\u306b\u98df\u54c1\u7d20\u6750\u3068\u3057\u3066\u5e02\u8ca9\u3055\u308c\u3066\u304a\u308a\u3001\u4eca\u5f8c\u30d2\u30c8\u3067\u306e\u6709\u52b9\u6027\u304c\u660e\u3089\u304b\u306b\u306a\u308c\u3070\u3001\u7518\u3055\u3092\u6211\u6162\u305b\u305a\u306b\u5065\u5eb7\u3092\u7dad\u6301\u3059\u308b\u65b0\u305f\u306a\u9078\u629e\u80a2\u3068\u306a\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/u><\/p>\r\n<p>&nbsp;<\/p>\r\n<p>\u672c\u7814\u7a76\u6210\u679c\u306f\u3001\u30b9\u30a4\u30b9\u306e\u5b66\u8853\u96d1\u8a8c\u300cInternational Journal of Molecular Sciences\u300d\u306b\u63b2\u8f09\u3055\u308c\u30012026\u5e742\u67088\u65e5\u306b\u30aa\u30f3\u30e9\u30a4\u30f3\u3067\u767a\u8868\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\r\n<p>\u3010\u6982\u8981\u56f3\u3011<\/p>\r\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-medium wp-image-2914 colorbox-2910\" src=\"https:\/\/kpu-als.jp\/w\/wp-content\/uploads\/2026\/02\/5ba897d6d697425ab4b38f14e988b482-450x348.png\" alt=\"\" width=\"450\" height=\"348\" srcset=\"https:\/\/kpu-als.jp\/w\/wp-content\/uploads\/2026\/02\/5ba897d6d697425ab4b38f14e988b482-450x348.png 450w, https:\/\/kpu-als.jp\/w\/wp-content\/uploads\/2026\/02\/5ba897d6d697425ab4b38f14e988b482.png 574w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/p>\r\n<p>\u3010\u8ad6\u6587\u60c5\u5831\u3011<\/p>\r\n<p>\u8ad6\u6587\u540d\uff1a GLP-1 Release by Rare Sugar D-Allulose Ameliorates Sucrose-Induced Obesity and Glucose Intolerance in Ovariectomized Mice<\/p>\r\n<p>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff08\u5e0c\u5c11\u7cd6D-\u30a2\u30eb\u30ed\u30fc\u30b9\u306b\u3088\u308bGLP-1\u5206\u6ccc\u306f\u3001\u5375\u5de3\u6458\u51fa\u30de\u30a6\u30b9\u306b\u304a\u3051\u308b\u30b7\u30e7\u7cd6\u8a98\u767a\u6027\u80a5\u6e80\u304a\u3088\u3073\u8010\u7cd6\u80fd\u969c\u5bb3\u3092\u6539\u5584\u3059\u308b\uff09<\/p>\r\n<p>\u8457\u8005\uff1a\u00a0\u00a0\u00a0 Kengo Iba, Miharu Kyo, Hirotaka Ishihara, Aki Nagao, Misaki Kawabe, Kento Ohbayashi, Toshihiko Yada, and Yusaku Iwasaki*.\uff08*\u4ee3\u8868\u8457\u8005\uff09<\/p>\r\n<p>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u5c04\u5834\u62f3\u864e\u3001\u4eac\u7f8e\u6674\u3001\u77f3\u539f\u5bdb\u9686\u3001\u6c38\u5c3e\u4e9c\u5e0c\u3001\u6cb3\u9089\u5b9f\u54b2\u3001\u5927\u6797\u5065\u4eba\u3001\u77e2\u7530\u4fca\u5f66\u3001\u5ca9\ufa11\u6709\u4f5c<\/p>\r\n<p>\u96d1\u8a8c\u540d\uff1a <strong><em>International Journal of Molecular Sciences<\/em><\/strong>, 27, 1651 (2026)<\/p>\r\n<p>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <a href=\"https:\/\/www.mdpi.com\/1422-0067\/27\/4\/1651\">https:\/\/www.mdpi.com\/1422-0067\/27\/4\/1651<\/a><\/p>\r\n<p>\u3010\u5927\u5b66HP\u3011<\/p>\r\n<p><a href=\"https:\/\/www.kpu.ac.jp\/news\/kenkyuuseika20251114-16972-72061-16666-84114\/\">https:\/\/www.kpu.ac.jp\/news\/kenkyuuseika20251114-16972-72061-16666-84114\/<\/a><\/p>\r\n<p>\u3010\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\uff08\u7814\u7a76\u6982\u7565\u306e\u539f\u7a3f\uff09\u3011<\/p>\r\n<p><a href=\"https:\/\/kpu-als.jp\/w\/wp-content\/uploads\/2026\/02\/20260213PressreleaseR1.pdf\">20260213PressreleaseR1<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>\u9589\u7d4c\u5f8c\u306e\u904e\u5270\u306a\u7802\u7cd6\u6442\u53d6\u306f\u5185\u81d3\u80a5\u6e80\u30682\u578b\u7cd6\u5c3f\u75c5\u3092\u5897\u60aa\u3055\u305b\u308b\u3053\u3068\u3092\u767a\u898b\uff01 \u305d\u3057\u3066\u3001\u3053\u306e\u4e88\u9632\u306b\u5e0c\u5c11\u7cd6\u30a2\u30eb\u30ed\u30fc\u30b9\u304c\u6709\u52b9\uff01 &nbsp; \u5e73\u5747\u3057\u306650\u6b73\u524d\u5f8c\u3067\u8fce\u3048\u308b\u9589\u7d4c\u306b\u4f34\u3046\u5973\u6027\u30db\u30eb\u30e2\u30f3\uff1a\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u306e\u4f4e\u4e0b\u306f\u3001\u5185\u81d3\u8102\u80aa\u306e\u84c4\u7a4d\u3092\u4fc3\u9032 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[6],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/posts\/2910"}],"collection":[{"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/comments?post=2910"}],"version-history":[{"count":3,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/posts\/2910\/revisions"}],"predecessor-version":[{"id":2923,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/posts\/2910\/revisions\/2923"}],"wp:attachment":[{"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/media?parent=2910"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/categories?post=2910"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/tags?post=2910"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}