{"id":2821,"date":"2025-05-24T10:18:43","date_gmt":"2025-05-24T01:18:43","guid":{"rendered":"https:\/\/kpu-als.jp\/w\/?p=2821"},"modified":"2025-05-28T10:39:40","modified_gmt":"2025-05-28T01:39:40","slug":"%e8%a9%b1%e9%a1%8c%e3%81%ae%e8%85%b8%e3%83%9b%e3%83%ab%e3%83%a2%e3%83%b3glp-1%e3%81%ae%e9%a3%9f%e6%ac%b2%e8%aa%bf%e7%af%80%e4%bd%9c%e7%94%a8%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6%e7%b7%8f%e8%aa%ac","status":"publish","type":"post","link":"https:\/\/kpu-als.jp\/w\/2025\/05\/%e8%a9%b1%e9%a1%8c%e3%81%ae%e8%85%b8%e3%83%9b%e3%83%ab%e3%83%a2%e3%83%b3glp-1%e3%81%ae%e9%a3%9f%e6%ac%b2%e8%aa%bf%e7%af%80%e4%bd%9c%e7%94%a8%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6%e7%b7%8f%e8%aa%ac\/","title":{"rendered":"\u8a71\u984c\u306e\u8178\u30db\u30eb\u30e2\u30f3GLP-1\u306e\u98df\u6b32\u8abf\u7bc0\u4f5c\u7528\u306b\u3064\u3044\u3066\u7dcf\u8aac\u3092\u767a\u8868\u3057\u307e\u3057\u305f\uff08\u52d5\u7269\u6a5f\u80fd\u5b66\uff09"},"content":{"rendered":"<p><strong>\u8a71\u984c\u306e\u8178\u30db\u30eb\u30e2\u30f3\u300c\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\uff08<\/strong><strong>GLP-1<\/strong><strong>\uff09\u300d\u306e\u98df\u6b32\u306b\u5bfe\u3059\u308b\u52b9\u679c<\/strong><\/p>\r\n<p>\u793e\u4f1a\u7684\u80cc\u666f\u3068\u3057\u3066\u3001\u4e16\u754c\u898f\u6a21\u3067\u80a5\u6e80\u306f\u5897\u52a0\u3057\u7d9a\u3051\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u80a5\u6e80\u306e\u4e3b\u306a\u539f\u56e0\u306f\u904e\u98df\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u7f8e\u5473\u3057\u3044\u3082\u306e\u3092\u624b\u306b\u5165\u308c\u3089\u308c\u308b\u73fe\u4ee3\u3001\u904e\u98df\u3092\u6291\u5236\u30fb\u4e88\u9632\u3059\u308b\u3053\u3068\u306f\u5bb9\u6613\u3067\u306a\u304f\u3001\u533b\u85ac\u54c1\u5206\u91ce\u306b\u304a\u3051\u308b\u6442\u98df\u6291\u5236\u85ac\u306e\u958b\u767a\u3082\u96e3\u822a\u3057\u3066\u304d\u307e\u3057\u305f\u3002<\/p>\r\n<p>\u6628\u5e74\u304b\u3089\u3001\u8178\u7531\u6765\u306e\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\uff08GLP-1\uff09\u304c\u8a71\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u7406\u7531\u306f\u3001\u6628\u5e74\u65e5\u672c\u3067\u306f30\u5e74\u3076\u308a\u306b\u3001\u6297\u80a5\u6e80\u85ac\uff08\u98df\u6b32\u6291\u5236\u85ac\uff09\u304c\u4f7f\u7528\u958b\u59cb\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u3053\u306e\u65b0\u3057\u3044\u85ac\u306f\u3001GLP-1\u3092\u57fa\u306b\u3057\u3066\u8a2d\u8a08\u3055\u308c\u305fGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u3044\u3046\u3082\u306e\u3067\u3059\u3002\u4e00\u65b9\u3001\u8178\u30db\u30eb\u30e2\u30f3GLP-1\u306f\u6211\u3005\u306e\u8178\u304b\u3089\u98df\u5f8c\u306b\u5206\u6ccc\u3055\u308c\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3059\u3002\u8178\u7531\u6765\u306eGLP-1\u3068GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u975e\u5e38\u306b\u985e\u4f3c\u3067\u3042\u308b\u3053\u3068\u304b\u3089\u3001\u98df\u4e8b\u3067\u8a98\u5c0e\u3055\u308c\u308b\u8178GLP-1\u3092\u9069\u5207\u306b\u5229\u7528\u3059\u308c\u3070\u3001\u6297\u80a5\u6e80\u85ac\u306e\u3088\u3046\u306b\u3001\u904e\u98df\u3084\u80a5\u6e80\u3092\u4e88\u9632\u30fb\u6539\u5584\u3067\u304d\u308b\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\r\n<p>\u5b66\u8853\u96d1\u8a8c\u300cDiabetology International\u300d\u306b\u767a\u8868\u3057\u307e\u3057\u305f\u672c\u7dcf\u8aac\u3067\u306f\u3001\u8178\u7531\u6765\u306eGLP-1\u3068GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u300c\u98df\u6b32\u306b\u5bfe\u3059\u308b\u4f5c\u7528\u300d\u3068\u300c\u305d\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u300d\u3092\u6982\u8aac\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u526f\u4f5c\u7528\u306e\u767a\u751f\u8981\u56e0\u3092\u6574\u7406\u3059\u308b\u3068\u3068\u3082\u306b\u3001\u4e21\u8005\u306e\u7279\u6027\u3092\u6d3b\u304b\u3057\u305f\u4f75\u7528\u6226\u7565\u306e\u53ef\u80fd\u6027\u3092\u8ad6\u3058\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u8178GLP-1\u304c\u6709\u3059\u308b\u300c\u526f\u4f5c\u7528\u306a\u304f\u81ea\u7136\u306b\u98df\u6b32\u3092\u6291\u3048\u308b\u300d\u52b9\u679c\u306b\u7740\u76ee\u3057\u3001\u7279\u5b9a\u306eGLP-1\u5206\u6ccc\u3092\u4fc3\u9032\u3055\u305b\u308b\u98df\u6750\uff08\u5e0c\u5c11\u7cd6\u306a\u3069\uff09\u3084\u98df\u4e8b\u306e\u9806\u756a\u306e\u5de5\u592b\u306b\u3088\u3063\u3066\u3001\u8178GLP-1\u306e\u751f\u7406\u7684\u5206\u6ccc\u3092\u9ad8\u3081\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u89e3\u8aac\u3057\u3066\u3044\u307e\u3059\u3002\u8178GLP-1\u5206\u6ccc\u4fc3\u9032\u3068GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u3092\u4f75\u7528\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u305d\u308c\u305e\u308c\u306e\u77ed\u6240\u3092\u88dc\u5b8c\u3057\u5408\u3044\u306a\u304c\u3089\u3001\u9577\u671f\u7684\u306a\u80a5\u6e80\u4e88\u9632\u30fb\u6cbb\u7642\u306b\u8ca2\u732e\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\r\n<p>\u82f1\u8a9e\u306e\u7dcf\u8aac\u8ad6\u6587\u3068\u306a\u308a\u307e\u3059\u304c\u3001\u3054\u8208\u5473\u3092\u304a\u6301\u3061\u306e\u65b9\u306f\u3001\u305c\u3072\u3054\u4e00\u8aad\u3044\u305f\u3060\u3051\u307e\u3059\u3068\u5e78\u3044\u3067\u3059\u3002<\/p>\r\n<p>\u3010\u8ad6\u6587\u60c5\u5831\u3011<\/p>\r\n<p>\u8ad6\u6587\u540d\uff1a\u00a0\u00a0 Comparing the anorexigenic effects and mechanisms of gut-derived GLP-1 and its receptor agonists: insights into incretin-based therapies for obesity<\/p>\r\n<p>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \uff08\u8178\u7531\u6765GLP-1\u3068\u305d\u306e\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u98df\u6b32\u6291\u5236\u4f5c\u7528\u3068\u4f5c\u7528\u6a5f\u5e8f\u306e\u6bd4\u8f03\uff1a\u80a5\u6e80\u6cbb\u7642\u306b\u304a\u3051\u308b\u30a4\u30f3\u30af\u30ec\u30c1\u30f3\u7642\u6cd5\u306e\u65b0\u305f\u306a\u5c55\u671b\uff09<\/p>\r\n<p>&nbsp;<\/p>\r\n<p>\u8457\u8005\uff1a \u00a0\u00a0\u00a0 Yuta Masuda\uff08\u5897\u7530\u96c4\u592a\uff09, Kento Ohbayashi\uff08\u5927\u6797\u5065\u4eba\uff09and Yusaku Iwasaki*\uff08\u5ca9\u5d0e\u6709\u4f5c\u3001*\u4ee3\u8868\u8457\u8005\uff09<\/p>\r\n<p>&nbsp;<\/p>\r\n<p>\u96d1\u8a8c\u540d\uff1a\u00a0\u00a0 Diabetology International, (2025)<\/p>\r\n<p>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <a href=\"https:\/\/doi.org\/10.1007\/s13340-025-00819-9\">https:\/\/doi.org\/10.1007\/s13340-025-00819-9<\/a><\/p>\r\n<p>&nbsp;<\/p>\r\n<p>\u3010\u6982\u8981\u56f3\u3011<\/p>\r\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-medium wp-image-2822 colorbox-2821\" src=\"https:\/\/kpu-als.jp\/w\/wp-content\/uploads\/2025\/05\/29d3bc99193cb0b837fb8cc53f050ae5-450x244.png\" alt=\"\" width=\"450\" height=\"244\" srcset=\"https:\/\/kpu-als.jp\/w\/wp-content\/uploads\/2025\/05\/29d3bc99193cb0b837fb8cc53f050ae5-450x244.png 450w, https:\/\/kpu-als.jp\/w\/wp-content\/uploads\/2025\/05\/29d3bc99193cb0b837fb8cc53f050ae5-800x433.png 800w, https:\/\/kpu-als.jp\/w\/wp-content\/uploads\/2025\/05\/29d3bc99193cb0b837fb8cc53f050ae5.png 850w\" sizes=\"(max-width: 450px) 100vw, 450px\" \/><\/p>","protected":false},"excerpt":{"rendered":"<p>\u8a71\u984c\u306e\u8178\u30db\u30eb\u30e2\u30f3\u300c\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9\uff08GLP-1\uff09\u300d\u306e\u98df\u6b32\u306b\u5bfe\u3059\u308b\u52b9\u679c \u793e\u4f1a\u7684\u80cc\u666f\u3068\u3057\u3066\u3001\u4e16\u754c\u898f\u6a21\u3067\u80a5\u6e80\u306f\u5897\u52a0\u3057\u7d9a\u3051\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u80a5\u6e80\u306e\u4e3b\u306a\u539f\u56e0\u306f\u904e\u98df\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u7f8e\u5473\u3057\u3044\u3082\u306e\u3092\u624b\u306b\u5165\u308c\u3089\u308c\u308b\u73fe\u4ee3\u3001\u904e\u98df\u3092\u6291\u5236\u30fb\u4e88\u9632 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[7,6],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/posts\/2821"}],"collection":[{"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/comments?post=2821"}],"version-history":[{"count":2,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/posts\/2821\/revisions"}],"predecessor-version":[{"id":2826,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/posts\/2821\/revisions\/2826"}],"wp:attachment":[{"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/media?parent=2821"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/categories?post=2821"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/tags?post=2821"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}