{"id":2016,"date":"2021-06-11T08:49:27","date_gmt":"2021-06-10T23:49:27","guid":{"rendered":"https:\/\/kpu-als.jp\/w\/?p=2016"},"modified":"2021-06-11T08:49:48","modified_gmt":"2021-06-10T23:49:48","slug":"%e8%83%83%e8%85%b8%e4%bc%b8%e5%b1%95%e5%88%ba%e6%bf%80%e3%81%ab%e3%82%88%e3%82%8b%e6%9c%89%e7%9b%8a%e4%bd%9c%e7%94%a8%e3%81%a8%e3%81%9d%e3%81%ae%e4%bd%9c%e7%94%a8%e6%a9%9f%e5%ba%8f%e3%82%92%e8%a7%a3","status":"publish","type":"post","link":"https:\/\/kpu-als.jp\/w\/2021\/06\/%e8%83%83%e8%85%b8%e4%bc%b8%e5%b1%95%e5%88%ba%e6%bf%80%e3%81%ab%e3%82%88%e3%82%8b%e6%9c%89%e7%9b%8a%e4%bd%9c%e7%94%a8%e3%81%a8%e3%81%9d%e3%81%ae%e4%bd%9c%e7%94%a8%e6%a9%9f%e5%ba%8f%e3%82%92%e8%a7%a3\/","title":{"rendered":"\u80c3\u8178\u4f38\u5c55\u523a\u6fc0\u306b\u3088\u308b\u6709\u76ca\u4f5c\u7528\u3068\u305d\u306e\u4f5c\u7528\u6a5f\u5e8f\u3092\u89e3\u660e\uff08\u52d5\u7269\u6a5f\u80fd\u5b66\uff09"},"content":{"rendered":"<u>\u80c3\u8178\u4f38\u5c55\u306f\u3001\u8178\u30db\u30eb\u30e2\u30f3<span>GLP-1<\/span>\u306e\u5206\u6ccc\u4fc3\u9032\u3068\u3001\u5185\u81d3\u611f\u899a\u795e\u7d4c\u3092\u4ecb\u3057\u305f\u8133\u4f5c\u7528\u306b\u3088\u3063\u3066\u3001\u98df\u3079\u904e\u304e\u30fb\u30c0\u30e9\u30c0\u30e9\u98df\u3044\u30fb\u98df\u5f8c\u9ad8\u8840\u7cd6\u30fb\u80a5\u6e80\u3092\u6539\u5584\u3059\u308b<\/u>\r\n\r\n&nbsp;\r\n\r\n\u80a5\u6e80\u306f\u3001\u7cd6\u5c3f\u75c5\u3084\u9ad8\u8840\u5727\u306a\u3069\u306e\u751f\u6d3b\u7fd2\u6163\u75c5\u767a\u75c7\u306e\u4e3b\u305f\u308b\u539f\u56e0\u3068\u306a\u308a\u307e\u3059\u3002\u80a5\u6e80\u306e\u4e88\u9632\u30fb\u6cbb\u7642\u306e\u305f\u3081\u306e\u98df\u4e8b\u6cd5\u3068\u3057\u3066\u3001\u30b5\u30e9\u30c0\u306a\u3069\u306e\u30dc\u30ea\u30e5\u30fc\u30e0\u304c\u3042\u308a\u4f4e\u30ab\u30ed\u30ea\u30fc\u306a\u98df\u54c1\u304b\u3089\u98df\u3079\u59cb\u3081\u308b\u65b9\u6cd5\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u6a5f\u5e8f\u3068\u3057\u3066\u3001\u80c3\u8178\u306e\u4f38\u5c55\u304c\u6e80\u8179\u611f\u3092\u8a98\u5c0e\u3059\u308b\u3068\u3044\u3046\u5148\u884c\u7814\u7a76\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u306e\u8a73\u7d30\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u6982\u306d\u4e0d\u660e\u3067\u3057\u305f\u3002\u80c3\u8178\u4f38\u5c55\u306e\u751f\u7406\u6a5f\u80fd\u89e3\u6790\u7814\u7a76\u304c\u7acb\u3061\u9045\u308c\u3066\u3044\u305f\u7406\u7531\u306e<span>1<\/span>\u3064\u306b\u3001\u5b9f\u9a13\u7684\u306b\u80c3\u8178\u3092\u4f38\u5c55\u3055\u305b\u308b\u65b9\u6cd5\u306b\u554f\u984c\u304c\u3042\u308a\u307e\u3057\u305f\u3002\u3053\u308c\u307e\u3067\u306e\u80c3\u8178\u4f38\u5c55\u6cd5\u3068\u3057\u3066\u306f\u3001\u5916\u79d1\u624b\u8853\u3092\u7528\u3044\u3066\u80c3\u8178\u5185\u306b\u98a8\u8239\u7b49\u3092\u5165\u308c\u308b\u65b9\u6cd5\u304c\u4e00\u822c\u7684\u3067\u3001\u3053\u308c\u3089\u5916\u79d1\u624b\u8853\u304c\u305d\u306e\u5f8c\u306e\u751f\u7406\u7684\u306a\u884c\u52d5\u89e3\u6790\uff08\u98df\u884c\u52d5\u3084\u7cd6\u4ee3\u8b1d\u89e3\u6790\uff09\u306b\u5236\u9650\u3092\u304b\u3051\u3066\u3044\u307e\u3057\u305f\u3002\r\n\r\n\u4eca\u56de\u3001\u4eac\u90fd\u5e9c\u7acb\u5927\u5b66\u5927\u5b66\u9662\u751f\u547d\u74b0\u5883\u79d1\u5b66\u7814\u7a76\u79d1\u306e\u5ca9\ufa11\u6709\u4f5c\u6559\u6388\u3068\u5927\u5b66\u9662\u751f\u306e\u5927\u6797\u5065\u4eba\u3089\u306e\u30c1\u30fc\u30e0\u306f\u3001\u95a2\u897f\u96fb\u529b\u533b\u5b66\u7814\u7a76\u6240\u77e2\u7530\u4fca\u5f66\u90e8\u9577\u3001\u5927\u6b63\u88fd\u85ac\u682a\u5f0f\u4f1a\u793e\u3068\u306e\u5171\u540c\u7814\u7a76\u3067\u3001\u80c3\u306e\u9178\u6027\u6761\u4ef6\u4e0b\u3067\u30b2\u30eb\u72b6\u306e\u6c17\u6ce1\u3092\u5f62\u6210\u3059\u308b\u300c\u30da\u30af\u30c1\u30f3\u542b\u6709\u70ad\u9178\u6c34\u300d\u3092\u7528\u3044\u3066\u80c3\u8178\u3092\u4f38\u5c55\u3055\u305b\u3001\u80c3\u8178\u4f38\u5c55\u306b\u3088\u308b\u6e80\u8179\u611f\u8a98\u5c0e\u4f5c\u7528\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u4f5c\u7528\u306e\u5897\u5f37\u306b\u3088\u308b\u98df\u5f8c\u9ad8\u8840\u7cd6\u6539\u5584\u4f5c\u7528\u3092\u3001\u30de\u30a6\u30b9\u3092\u7528\u3044\u305f\u5b9f\u9a13\u306b\u3088\u3063\u3066\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f<span> [<\/span>\u6982\u8981\u56f3<span>]<\/span>\u3002<span>2010<\/span>\u5e74\u304b\u3089\u6211\u304c\u56fd\u3067\u65b0\u3057\u304f\u5229\u7528\u3055\u308c\u3066\u3044\u308b\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u306e<span>GLP-1<\/span>\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u3001\u8178\u30db\u30eb\u30e2\u30f3<span>GLP-1<\/span>\uff08\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9<span>-1<\/span>\uff09\u3092\u92f3\u578b\u3068\u3057\u305f\u88fd\u5264\u3067\u3059\u3002\u4eca\u56de\u767a\u898b\u3057\u305f\u80c3\u8178\u4f38\u5c55\u306b\u3088\u308b\u751f\u7406\u4f5c\u7528\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3001\u80c3\u8178\u4f38\u5c55\u306b\u3088\u308b<span>GLP-1<\/span>\u5206\u6ccc\u306e\u4fc3\u9032\u304c\u5927\u304d\u304f\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f<span> [<\/span>\u6982\u8981\u56f3<span>]<\/span>\u3002\u3055\u3089\u306b\u3001<span>GLP-1<\/span>\u304c\u5185\u81d3\u611f\u899a\u795e\u7d4c\uff08\u6c42\u5fc3\u6027\u8ff7\u8d70\u795e\u7d4c\uff09\u3092\u4ecb\u3057\u3066\u8133\u795e\u7d4c\u7cfb\u306b\u4f5c\u7528\u3059\u308b\u3053\u3068\u3082\u91cd\u8981\u3067\u3042\u308a\u307e\u3057\u305f\u3002\u6e80\u8179\u611f\u3092\u8a98\u5c0e\u3059\u308b\u30da\u30af\u30c1\u30f3\u542b\u6709\u70ad\u9178\u6c34\u3092\u3001\u80a5\u6e80\u30de\u30a6\u30b9\u3078\u6bce\u65e5\u4e0e\u3048\u308b\u3068\u3001\u30c0\u30e9\u30c0\u30e9\u98df\u3044\uff08\u6442\u98df\u30ea\u30ba\u30e0\u7570\u5e38\uff09\u3092\u662f\u6b63\u3057\u3001\u80a5\u6e80\u3092\u6539\u5584\u3057\u307e\u3057\u305f <span>[<\/span>\u6982\u8981\u56f3<span>]<\/span>\u3002\r\n\r\n\u672c\u6210\u679c\u306f\u3001\u80c3\u8178\u4f38\u5c55\u523a\u6fc0\u304c\u80a5\u6e80\u3084\u7cd6\u5c3f\u75c5\u6cbb\u7642\u306b\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u3001\u3055\u3089\u306b\u3001\u305d\u306e\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u4e00\u7aef\u3092\u660e\u3089\u304b\u3068\u3057\u307e\u3057\u305f\u3002\u672c\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u5fdc\u7528\u3057\u305f\u65b0\u305f\u306a\u80a5\u6e80\u30fb\u7cd6\u5c3f\u75c5\u306e\u4e88\u9632\u30fb\u6cbb\u7642\u6cd5\uff08\u6a5f\u80fd\u6027\u98df\u54c1\u3001\u85ac\uff09\u306e\u958b\u767a\u304c\u4eca\u5f8c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\r\n\r\n\u672c\u7814\u7a76\u6210\u679c\u306f\u3001<span>2021<\/span>\u5e74<span>6<\/span>\u6708<span>8<\/span>\u65e5\u306b\u30b9\u30a4\u30b9\u306e\u30aa\u30f3\u30e9\u30a4\u30f3\u5b66\u8853\u96d1\u8a8c\u300c<span>Frontiers in Endocrinology<\/span>\u300d\u8a8c\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002\r\n\r\n&nbsp;\r\n\r\n<a href=\"https:\/\/kpu-als.jp\/w\/wp-content\/uploads\/2021\/06\/1417ffba346364179d0937153ef79efd.bmp\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/kpu-als.jp\/w\/wp-content\/uploads\/2021\/06\/1417ffba346364179d0937153ef79efd-350x450.bmp\" alt=\"\" width=\"350\" height=\"450\" class=\"alignnone size-medium wp-image-2018 colorbox-2016\" srcset=\"https:\/\/kpu-als.jp\/w\/wp-content\/uploads\/2021\/06\/1417ffba346364179d0937153ef79efd-350x450.bmp 350w, https:\/\/kpu-als.jp\/w\/wp-content\/uploads\/2021\/06\/1417ffba346364179d0937153ef79efd.bmp 574w\" sizes=\"(max-width: 350px) 100vw, 350px\" \/><\/a>\r\n\r\n&nbsp;\r\n\r\n\u8457\u8005\uff1a<span>Kento Ohbayashi, Yukiko Oyama, Chiharu Yamaguchi, Toshiki Asano, Toshihiko Yada, Yusaku Iwasaki<\/span>\r\n\r\n\u8ad6\u6587\u540d\uff1a<span>Gastrointestinal distension by pectin-containing carbonated solution suppresses food intake and enhances glucose tolerance via GLP-1 secretion and vagal afferent activation.<\/span>\r\n\r\n\u96d1\u8a8c\uff1aFrontiers in Endocrinology, 12:6768695 (2021)\r\n\r\nURL\uff1a<span><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2021.676869\/full\">https:\/\/www.frontiersin.org\/articles\/10.3389\/fendo.2021.676869\/full<\/a><\/span>","protected":false},"excerpt":{"rendered":"<p>\u80c3\u8178\u4f38\u5c55\u306f\u3001\u8178\u30db\u30eb\u30e2\u30f3GLP-1\u306e\u5206\u6ccc\u4fc3\u9032\u3068\u3001\u5185\u81d3\u611f\u899a\u795e\u7d4c\u3092\u4ecb\u3057\u305f\u8133\u4f5c\u7528\u306b\u3088\u3063\u3066\u3001\u98df\u3079\u904e\u304e\u30fb\u30c0\u30e9\u30c0\u30e9\u98df\u3044\u30fb\u98df\u5f8c\u9ad8\u8840\u7cd6\u30fb\u80a5\u6e80\u3092\u6539\u5584\u3059\u308b &nbsp; \u80a5\u6e80\u306f\u3001\u7cd6\u5c3f\u75c5\u3084\u9ad8\u8840\u5727\u306a\u3069\u306e\u751f\u6d3b\u7fd2\u6163\u75c5\u767a\u75c7\u306e\u4e3b\u305f\u308b\u539f\u56e0\u3068\u306a\u308a\u307e\u3059\u3002\u80a5\u6e80\u306e [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false},"categories":[6],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/posts\/2016"}],"collection":[{"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/comments?post=2016"}],"version-history":[{"count":1,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/posts\/2016\/revisions"}],"predecessor-version":[{"id":2019,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/posts\/2016\/revisions\/2019"}],"wp:attachment":[{"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/media?parent=2016"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/categories?post=2016"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kpu-als.jp\/w\/wp-json\/wp\/v2\/tags?post=2016"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}